Advances in Optical Diagnostics and Therapy for Head and Neck Cancer
Author Information
Author(s): Upile Tahwinder, Jerjes Waseem K, Sterenborg Henricus J, Wong Brian J, El-Naggar Adel K, Ilgner Justus F, Sandison Ann, Witjes Max J, Biel Merrill A, van Veen Robert, Hamdoon Zaid, Gillenwater Ann, Mosse Charles A, Robinson Dominic J, Betz Christian S, Stepp Herbert, Bolotine Lina, McKenzie Gordon, Barr Hugh, Chen Zhongping, Berg Kristian, D'Cruz Anil K, Sudhoff Holger, Stone Nicholas, Kendall Catherine, Fisher Sheila, MacRobert Alexander J, Leunig Andreas, Olivo Malini, Richards-Kortum Rebecca, Soo Khee C, Bagnato Vanderlei, Choo-Smith Lin-Ping, Svanberg Katarina, Tan I Bing, Wilson Brian C, Wolfsen Herbert, Bigio Irving, Yodh Arjun G, Hopper Colin
Hypothesis
Can advances in optical diagnostic technology improve surgical outcomes in head and neck oncology?
Conclusion
Optical technologies show promise in improving disease detection and treatment outcomes in head and neck cancer.
Supporting Evidence
- Optical diagnostics have shown increased sensitivity and specificity compared to traditional methods.
- Fluorescence spectroscopy is already being used in clinical practice.
- Optical coherence tomography (OCT) has demonstrated high sensitivity and specificity for early tumor diagnosis.
- Studies indicate that optical technologies can reduce the workload of histopathology.
- Optical techniques can provide real-time, non-invasive assessments of tissue pathology.
Takeaway
Doctors are using special light technologies to find and treat cancers in the head and neck better, which can help save lives.
Methodology
The review summarizes various optical diagnostic techniques and their applications in head and neck oncology.
Limitations
Many techniques are still in clinical trials and not widely adopted in practice.
Digital Object Identifier (DOI)
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