Outbreak of Dengue and Chikungunya Fevers, Toamasina, Madagascar, 2006
2008

Outbreak of Dengue and Chikungunya Fevers in Madagascar

Sample size: 4242 publication Evidence: moderate

Author Information

Author(s): Ratsitorahina Mahery, Harisoa Julie, Ratovonjato Jocelyn, Biacabe Sophie, Reynes Jean-Marc, Zeller Hervé, Raoelina Yolande, Talarmin Antoine, Richard Vincent, Soares Jean Louis

Primary Institution: Institut Pasteur de Madagascar

Conclusion

An outbreak caused by both chikungunya and dengue viruses occurred in Madagascar, affecting a significant portion of the population.

Supporting Evidence

  • 67.5% of residents reported dengue-like symptoms during the outbreak.
  • Dengue virus and chikungunya virus were detected in 38 of 55 patients sampled.
  • Co-infections were found in 10 patients.
  • Aedes albopictus was the only mosquito vector identified.
  • The mean age of participants was 24.9 years.
  • 72.7% of participants reported more than one previous episode of fever.
  • High attack rates were observed among all age groups.

Takeaway

In Madagascar, many people got sick from two viruses called dengue and chikungunya, which spread through mosquito bites.

Methodology

A retrospective cross-sectional study was conducted with serum samples from patients and interviews of residents to assess the outbreak.

Potential Biases

Underreporting of cases, especially in children, may have affected the prevalence estimates.

Limitations

The study was based on clinical observations alone, which may not fully capture the extent of the outbreak.

Participant Demographics

The mean age of participants was 24.9 years, with a sex ratio of 0.87.

Statistical Information

P-Value

p<0.01

Confidence Interval

95% CI 24.4–25.4

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.3201/eid1407.071521

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