2-[4-(2-Methoxyphenyl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide
2011
Crystal Structure of a Compound Used in Imaging Agents
publication
Evidence: high
Author Information
Author(s): Lu Chunxiong, Jiang Quanfu
Primary Institution: Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine
Conclusion
The study presents the crystal structure of a compound that is an important intermediate in the synthesis of receptor imaging agents.
Supporting Evidence
- The compound is used in the synthesis of serotonin receptor imaging agents.
- The piperazine ring of the compound adopts a chair conformation.
- The study details intra- and intermolecular hydrogen-bonding interactions.
Takeaway
Scientists studied a special chemical compound to understand its structure, which helps in making imaging agents for medical use.
Methodology
The compound was synthesized and crystallized from a mixed solvent of acetone and water, and its structure was analyzed using X-ray diffraction.
Digital Object Identifier (DOI)
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