Using Pleth Variability Index to Detect Blood Flow Changes
Author Information
Author(s): Geoffray Keller, Emmanuel Cassar, Olivier Desebbe, Jean-Jacques Lehot, Maxime Cannesson
Primary Institution: Hospices Civils de Lyon, Groupement Hospitalier Est, Department of Anesthesiology and Intensive Care
Hypothesis
Can the Pleth Variability Index (PVI) detect hemodynamic changes induced by passive leg raising in spontaneously breathing volunteers?
Conclusion
PVI can detect hemodynamic changes induced by passive leg raising in spontaneously breathing volunteers, but it is a weak predictor of fluid responsiveness.
Supporting Evidence
- PVI decreased significantly from baseline to PLR and increased significantly from PLR to the semirecumbent position.
- 11 out of 25 volunteers were responders to PLR, showing a significant difference in PVI values.
- A threshold PVI value above 19% was a weak but significant predictor of response to PLR.
Takeaway
The study tested a new tool called PVI to see if it could tell when people's blood flow changed after lifting their legs. It worked, but not very well.
Methodology
A prospective observational study with 25 volunteers measuring PVI, heart rate, and arterial pressure during different body positions.
Potential Biases
Potential bias due to the non-randomized observational design.
Limitations
The study did not conduct real volume expansion and results may not apply to patients with cardiac arrhythmias.
Participant Demographics
12 females and 13 males aged between 21 and 55 years (mean age 30 ± 9 years).
Statistical Information
P-Value
0.058
Confidence Interval
0.734 ± 0.101
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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