Vitamin E and Glutathione Levels in Saliva of Children with Dental Caries
Author Information
Author(s): Muacevic Alexander, Adler John R, Hussein Pareehan M, Hussein Vian M
Primary Institution: Hawler Center, Erbil, IRQ
Hypothesis
Lower levels of antioxidants are associated with dental caries in children.
Conclusion
Children with dental caries have significantly lower levels of antioxidants like glutathione and vitamin E compared to those without caries.
Supporting Evidence
- Children with caries had a mean glutathione level of 1664.36 µM compared to 1945.36 µM in caries-free children.
- The mean vitamin E level in caries-active children was 4.08 nM, significantly lower than 5.32 nM in caries-free children.
- Statistical analysis showed significant differences in antioxidant levels between the two groups.
Takeaway
This study found that kids with cavities have less of certain good stuff in their saliva that helps keep their teeth healthy.
Methodology
This cross-sectional study evaluated salivary levels of glutathione and vitamin E in 90 children categorized by caries status.
Potential Biases
Potential biases due to convenience sampling and reliance on self-reported data.
Limitations
The cross-sectional design limits causal inference, and confounding factors were not fully controlled.
Participant Demographics
Children aged 6-12 years, with equal distribution of caries-active and caries-free participants.
Statistical Information
P-Value
0.009
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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