LIFE EXTENSION VIA GENETIC/DRUG INTERVENTIONS OCCURS BY DELAYING THE ONSET OF AGING, NOT BY SLOWING THE RATE OF AGING
2024
Delaying Aging Onset, Not Slowing Aging Rate
publication
Evidence: moderate
Author Information
Author(s): Patrick Phillips, Christine Sedore, Grace Jackson, Gordon Lithgow, Monica Driscoll
Primary Institution: University of Oregon
Hypothesis
Do genetic and chemical interventions increase lifespan by delaying the onset of aging rather than slowing the rate of aging?
Conclusion
The study found that interventions increase lifespan by delaying the onset of aging, not by slowing the aging process itself.
Supporting Evidence
- Aging is characterized by an accelerating decline in function and increased mortality.
- The study used a new framework to analyze the effects of interventions on aging.
- All treatments studied increased lifespan by delaying the onset of aging.
Takeaway
Scientists found that treatments can help you live longer by making you age slower at first, but they don't actually slow down aging later in life.
Methodology
The study analyzed various genetic and chemical interventions in C. elegans and mice to estimate mortality rates.
Digital Object Identifier (DOI)
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