Using NHANES oral health examination protocols as part of an esophageal cancer screening study conducted in a high-risk region of China
2007

Oral Health and Esophageal Cancer Screening in Rural China

Sample size: 718 publication Evidence: moderate

Author Information

Author(s): Bruce A Dye, Ru Wang, Ruth Lashley, Wenqiang Wei, Christian C Abnet, Guoqing Wang, Sanford M Dawsey, Wei Cong, Mark J Roth, Xiaojie Li, Youlin Qiao

Primary Institution: Centers for Disease Control and Prevention/National Center for Health Statistics

Hypothesis

What is the relationship between oral health and esophageal dysplasia in a high-risk region of China?

Conclusion

Poor oral health may be an important health problem and contributing factor to the prevalence of esophageal cancer in this population.

Supporting Evidence

  • 17% of participants were edentulous.
  • The mean DMFT score for the study population was 8.5.
  • 44.7% of participants had periodontal disease.
  • Participants with poor oral health were more likely to have esophageal dysplasia.

Takeaway

This study looked at how people's teeth and gums affect their risk of a serious throat disease in a part of China where many people get it.

Methodology

The study used NHANES oral health examination procedures and the Modified Gingival Index to assess oral health in participants aged 40-67 years in rural villages.

Potential Biases

Potential bias towards the selection of less healthy participants due to non-systematic random selection.

Limitations

The study group does not correspond to a random sample of the general population, which may limit the external validity of the findings.

Participant Demographics

Participants were adults aged 40-67 years from three rural villages in Linzhou, China, with a higher prevalence of esophageal cancer.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI 1.06, 2.39

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1472-6831-7-10

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