Biliary Diversion for Intractable Itching in a Child with Cholestasis
Author Information
Author(s): Ganesh Ramaswamy, Suresh Natarajan, Sathiyasekeran Malathi Ramachandran, Priya Kanchi
Primary Institution: Kanchi Kamakoti CHILDS Trust Hospital & The CHILDS Trust Medical Research Foundation, Nungambakkam, Chennai, India
Hypothesis
Can biliary diversion relieve intractable pruritus in children with progressive familial intrahepatic cholestasis type 1?
Conclusion
Biliary diversion successfully relieved the pruritus and improved the child's growth and overall condition.
Supporting Evidence
- The child had persistent jaundice and severe itching that did not respond to conventional medications.
- Post-surgery, the child experienced complete cessation of pruritus and improvement in growth.
- Ultrasound and liver biopsy confirmed the diagnosis of PFIC type 1.
Takeaway
A child with a severe itching problem due to a liver condition had surgery that helped stop the itching and made him grow better.
Methodology
The child underwent partial internal biliary diversion through a cholecystojejunocolic anastomosis.
Limitations
More studies and long-term follow-up are necessary before universal recommendation.
Participant Demographics
7-year-old male child with a history of jaundice and pruritus since infancy.
Digital Object Identifier (DOI)
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