N-[5-Methyl-2-(2-nitrophenyl)-4-oxo-1,3-thiazolidin-3-yl]pyridine-3-carboxamide monohydrate
2011
Study of a New Compound with Thiazolidinone and Pyridine-3-Carboxamide
publication
Evidence: moderate
Author Information
Author(s): Akkurt Mehmet, Çelik İsmail, Demir Hale, Özkırımlı Sumru, Büyükgüngör Orhan
Primary Institution: Erciyes University
Hypothesis
The combination of pyridine-3-carboxamide and thiazolidinone moieties will yield a compound with significant biological activity.
Conclusion
The new compound exhibits a stable crystal structure with notable intermolecular interactions.
Supporting Evidence
- The compound shows a dihedral angle of 85.8° between the benzene and pyridine rings.
- Intermolecular hydrogen bonds form a three-dimensional network in the crystal structure.
- Both enantiomers of the compound are statistically disordered in the unit cell.
Takeaway
Scientists created a new chemical compound by combining two known structures, and they found that it forms a stable crystal with interesting properties.
Methodology
The compound was synthesized through a reaction of specific chemicals and characterized using X-ray crystallography.
Digital Object Identifier (DOI)
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