Subpollen particles: carriers of allergenic proteins and oxidases
2007
How Pollen Fragments Affect Asthma
publication
Evidence: moderate
Author Information
Author(s): Bacsi A, Choudhury BK, Dharajiya N, Sur S, Boldogh I
Primary Institution: University of Texas Medical Branch
Hypothesis
Can sub-pollen particles reach the lower airways and contribute to asthma symptoms?
Conclusion
The study shows that sub-pollen particles can reach the lower airways and cause inflammation associated with seasonal asthma.
Supporting Evidence
- Ragweed pollen grains release sub-pollen particles that can reach the lower airways.
- Sub-pollen particles contain allergenic proteins and oxidase activity.
- Exposure to sub-pollen particles increases reactive oxygen species and airway inflammation.
Takeaway
Tiny pieces of pollen can get deep into our lungs and make asthma worse. Scientists think that using certain medicines might help reduce this problem.
Methodology
The study analyzed bronchial epithelial cells and used a mouse model to test the effects of sub-pollen particles.
Want to read the original?
Access the complete publication on the publisher's website