Study on Adiponectin and Resistin in South-Asians
Author Information
Author(s): Wasim Hanif, Nasser M Al-Daghri, Raja Chetty, Phillip G McTernan, A H Barnett, Sudhesh Kumar
Primary Institution: Queen Elizabeth Hospital, Birmingham University
Hypothesis
The study aims to determine the relationship between body fat distribution and adipocytokines in South-Asian subjects.
Conclusion
Resistin levels had an inverse correlation with adiponectin levels, indicating an inverse relationship between pro-inflammatory cytokines and adiponectin.
Supporting Evidence
- Adiponectin concentrations were highest in NGT, decreased in IGT, and lowest in DMT2.
- Leptin was significantly higher in DMT2 than IGT and NGT.
- There was a significant positive relationship between log adiponectin and 2-hr insulin values.
- There was a significant inverse correlation between log adiponectin and resistin.
Takeaway
This study looked at how certain proteins in the body relate to fat and sugar levels in South-Asians, finding that one protein goes down when another goes up.
Methodology
Cross-sectional study measuring serum adipocytokines, adiposity, insulinemia, and glucose tolerance levels in South-Asians.
Participant Demographics
150 South-Asians (80 males, 70 females) with varying glucose tolerance levels.
Statistical Information
P-Value
p < 0.01
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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