Building a Prostate Cancer Tissue Bank
Author Information
Author(s): Patel Ashokkumar A, Gilbertson John R, Parwani Anil V, Dhir Rajiv, Datta Milton W, Gupta Rajnish, Berman Jules J, Melamed Jonathan, Kajdacsy-Balla Andre, Orenstein Jan, Becich Michael J
Primary Institution: University of Pittsburgh
Hypothesis
The study aims to develop an informatics model for managing a prostate cancer tissue bank to support biomarker validation studies.
Conclusion
The Cooperative Prostate Cancer Tissue Resource (CPCTR) can effectively provide large volumes of well-annotated prostate tissue for research, aiding in biomarker validation and other studies.
Supporting Evidence
- The CPCTR has provided over 6,000 cases of prostate cancer specimens since its inception.
- The resource has implemented a centralized database for managing tissue samples and clinical data.
- Standardized protocols have been established for data collection and quality assurance.
Takeaway
The CPCTR is like a big library of prostate cancer samples that helps scientists study and find new ways to treat cancer.
Methodology
The study involved collecting and managing clinical data and tissue samples from multiple institutions using a centralized database and standardized protocols.
Potential Biases
Potential biases may arise from the diverse sources of tissue samples and varying local data collection practices.
Limitations
The study may face challenges in data integration and maintaining quality across multiple institutions.
Participant Demographics
The resource includes prostate cancer patients from various medical care settings across six states in the USA.
Digital Object Identifier (DOI)
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