Diagnosis of spontaneous bacterial peritonitis in infants and children with chronic liver disease: A cohort study
2011

Diagnosing Spontaneous Bacterial Peritonitis in Children with Liver Disease

Sample size: 30 publication Evidence: moderate

Author Information

Author(s): El-Shabrawi Mortada HF, El-Sisi Ola, Okasha Sawsan, Isa Mona, Elmakarem Sayed Abou, Eyada Iman, Abdel-Latif Zainab, El-Batran Gamal, Kamal Naglaa

Primary Institution: Cairo University

Hypothesis

Can spontaneous bacterial peritonitis (SBP) be diagnosed through routine ascitic fluid tapping in children with chronic liver disease?

Conclusion

SBP is common in children with chronic liver disease, and biochemical parameters of ascitic fluid improve diagnostic accuracy.

Supporting Evidence

  • Five patients were diagnosed with SBP, representing 16.7% of the sample.
  • Eight patients had culture negative neutrocytic ascites (CNNA), accounting for 26.7%.
  • The study found that fever was significantly more common in SBP and CNNA cases compared to negative cases.

Takeaway

Doctors can find out if kids with liver problems have a serious infection by checking their belly fluid.

Methodology

Thirty infants and children with chronic liver disease and ascites were studied, with ascitic fluid analyzed for various biochemical and bacteriological parameters.

Limitations

The study was limited to a small sample size and specific demographic.

Participant Demographics

Mean age of participants was 5.1 years, with 63.4% male and 36.6% female.

Statistical Information

P-Value

p = 0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1824-7288-37-26

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