Evaluating Endoscopic Treatments for Sessile Serrated Lesions
Author Information
Author(s): Kagemoto Kaizo, Okamoto Koichi, Okada Yasuyuki, sei Motoko, Fujimoto Shota, Yagi Mai, Mitsuhashi Takeshi, Ueda Hiroyuki, Yoshimoto Takanori, Kashihara Takanori, Kawaguchi Tomoyuki, Kida Yoshifumi, Mitsui Yasuhiro, Kawano Yutaka, Sogabe Masahiro, Miyamoto Hiroshi, Sato Yasushi, Muguruma Naoki, Takayama Tetsuji
Primary Institution: Tokushima University Graduate School
Hypothesis
What is the most suitable endoscopic treatment for sessile serrated lesions (SSL)?
Conclusion
Underwater endoscopic mucosal resection (UEMR) is a suitable treatment option for sessile serrated lesions, while cold snare polypectomy (CSP) results are pathologically insufficient.
Supporting Evidence
- The R0 resection rate was 87% for UEMR, 73% for EMR, and 42% for CSP.
- CSP specimens often contained no submucosal tissue, leading to inadequate resection.
- All four SSLD cases received R0 resection by EMR and UEMR.
Takeaway
Doctors looked at different ways to remove certain types of growths in the colon and found that one method works better than the others.
Methodology
This was a single-center retrospective study analyzing 92 sessile serrated lesions resected by EMR, CSP, and UEMR.
Potential Biases
Selection bias may exist due to the exclusion of fragmented or unstretched lesions.
Limitations
The study was conducted at a single institute with a small number of cases and utilized a retrospective design.
Participant Demographics
The study included 49 males and 43 females with a median age of 65 years.
Statistical Information
P-Value
0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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