Evolution of Sex-Specific Traits through Changes in HOX-Dependent doublesex Expression
2011

Evolution of Sex-Specific Traits in Drosophila

publication Evidence: high

Author Information

Author(s): Tanaka Kohtaro, Barmina Olga, Sanders Laura E., Arbeitman Michelle N., Kopp Artyom

Primary Institution: University of California–Davis

Hypothesis

How do changes in the expression of the doublesex gene contribute to the evolution of sex-specific traits in Drosophila?

Conclusion

The study shows that changes in the spatial regulation of the doublesex gene are crucial for the evolution of new sex-specific traits in Drosophila.

Supporting Evidence

  • Changes in the expression of the doublesex gene are linked to the development of sex-specific traits.
  • Spatial regulation of doublesex is essential for the proper development of male-specific structures.
  • Comparative analysis shows that the evolution of sex combs is associated with new expression domains of doublesex.

Takeaway

This study found that the way a gene called doublesex is turned on and off helps create different traits for male and female flies.

Methodology

The researchers analyzed the expression patterns of the doublesex gene and its interactions with the HOX gene Sex combs reduced in Drosophila.

Digital Object Identifier (DOI)

10.1371/journal.pbio.1001131

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