The association between diabetes mellitus, glucose, and chronic musculoskeletal complaints. Results from the Nord-Trøndelag Health Study
2008

Diabetes and Musculoskeletal Pain

Sample size: 64785 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hoff Ole M, Midthjell Kristian, Zwart John-Anker, Hagen Knut

Primary Institution: Norwegian University of Science and Technology

Hypothesis

Is there an association between diabetes mellitus, glucose levels, and chronic musculoskeletal complaints?

Conclusion

High non-fasting glucose is linked to lower prevalence of chronic musculoskeletal complaints, while diabetes mellitus is associated with higher prevalence of chronic widespread musculoskeletal complaints.

Supporting Evidence

  • High non-fasting glucose was associated with lower prevalence of chronic musculoskeletal complaints.
  • Individuals with diabetes were more likely to report chronic widespread musculoskeletal complaints.
  • The study included a large and unselected population, enhancing the reliability of the findings.

Takeaway

People with diabetes might have more pain in their muscles and joints, but those with higher blood sugar levels might feel less pain.

Methodology

Cross-sectional data from the Nord-Trøndelag Health Survey, using multiple logistic regression to assess associations.

Potential Biases

Potential selection bias regarding diabetes status and non-responders may skew results.

Limitations

The study may have recruitment bias and the self-reported nature of musculoskeletal complaints could affect accuracy.

Participant Demographics

Participants were adults aged 20 and above, with a mix of genders and diabetes types.

Statistical Information

P-Value

0.036

Confidence Interval

95% CI 1.2–2.2

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1471-2474-9-160

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