Impact of Coccidial Infection on Vaccine Response in Chickens
Author Information
Author(s): Kabell Susanne, Handberg Kurt J, Bisgaard Magne
Primary Institution: Danish Institute for Food and Veterinary Research
Hypothesis
Does coccidial infection affect the immune response to vaccination against IBDV in chickens?
Conclusion
Coccidia may enhance the immune response to IBDV vaccination in chickens.
Supporting Evidence
- Chickens with coccidia showed no clinical signs of disease during the study.
- Lesions consistent with coccidial infection were observed in infected groups.
- Vaccine strain IBDV was detected in lymphoid tissues of chickens infected with coccidia.
Takeaway
Chickens infected with coccidia might actually respond better to vaccines against a virus called IBDV.
Methodology
The study involved vaccinating SPF chickens, inoculating them with coccidia, and then challenging them with IBDV, followed by analysis of lymphoid tissues.
Limitations
The small sample sizes in each age group limited the reliability of statistical evaluations.
Participant Demographics
SPF chickens, three weeks old at the start of the experiment.
Digital Object Identifier (DOI)
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