Algal Functional Annotation Tool: a web-based analysis suite to functionally interpret large gene lists using integrated annotation and expression data
2011

Algal Functional Annotation Tool: A Web-Based Analysis Suite for Algal Genomics

publication Evidence: moderate

Author Information

Author(s): David Lopez, David Casero, Shawn J Cokus, Sabeeha S Merchant, Matteo Pellegrini

Primary Institution: University of California, Los Angeles

Hypothesis

The study aims to develop a comprehensive tool for the functional annotation of algal genomes.

Conclusion

The Algal Functional Annotation Tool provides an integrated environment for analyzing and interpreting large gene lists from algal genomic data.

Supporting Evidence

  • The tool integrates annotation data from various databases to provide comprehensive functional insights.
  • It allows users to interpret large gene lists and visualize them on KEGG pathway maps.
  • Expression data from multiple experimental conditions are included for enriched analysis.
  • Users can convert gene identifiers between different types to facilitate analysis.

Takeaway

This tool helps scientists understand what genes in algae do by organizing and analyzing a lot of information in one place.

Methodology

The tool integrates data from multiple biological databases and performs enrichment analysis on gene lists.

Limitations

The effectiveness of the tool is limited by the quality of annotations in the primary databases.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2105-12-282

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