Schistosomiasis transmission at high altitude crater lakes in Western Uganda
2008

Schistosomiasis Transmission in High Altitude Lakes of Uganda

Sample size: 370 publication Evidence: moderate

Author Information

Author(s): John Rubaihayo, Ezekiel Moghusu, Philbert Clouds, Andrew Abaasa

Primary Institution: Mountains of the Moon University

Hypothesis

Can schistosomiasis transmission occur at altitudes higher than 1,400 m in Uganda?

Conclusion

Schistosomiasis transmission can occur at altitudes higher than previously thought, posing a risk to communities using crater lakes for water.

Supporting Evidence

  • The overall prevalence of Schistosoma mansoni infection was 27.8% among the pupils studied.
  • 84.6% of the crater lakes studied were found to be infective.
  • Prevalence was highest in the age group 12-14 years at 49.5%.
  • The study found significant associations between altitude, water source, and infection rates.

Takeaway

This study found that kids using water from high-altitude lakes in Uganda can get a disease called schistosomiasis, which was thought to only happen at lower altitudes.

Methodology

An epidemiological survey was conducted among school children around 13 high altitude crater lakes, collecting stool samples and demographic data.

Potential Biases

Potential bias due to reliance on self-reported awareness and knowledge of the disease.

Limitations

The study could not establish temporal and spatial variability of abiotic factors affecting transmission.

Participant Demographics

Primary school pupils aged 6-18 years from communities around high altitude crater lakes.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 19.7–33.0%

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2334-8-110

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