3-Hydroxy-2-[(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)(thiophen-3-yl)methyl]-5,5-dimethylcyclohex-2-en-1-one
2011
Crystal Structure of a New Compound
publication
Evidence: moderate
Author Information
Author(s): Asad Mohammad, Oo Chuan-Wei, Osman Hasnah, Rosli Mohd Mustaqim, Fun Hoong-Kun
Primary Institution: Universiti Sains Malaysia
Hypothesis
The study investigates the crystal structure of a bis compound synthesized from thiophene-3-carboxaldehyde and dimedone.
Conclusion
The crystal structure reveals two independent molecules stabilized by intramolecular and intermolecular hydrogen bonds.
Supporting Evidence
- The compound was synthesized from thiophene-3-carboxaldehyde and dimedone.
- Two independent molecules were found in the asymmetric unit.
- Intramolecular hydrogen bonds stabilize the molecular structure.
- Intermolecular hydrogen bonds form dimers in the crystal structure.
Takeaway
The researchers created a new compound and looked at its structure using X-ray techniques, finding that it has two similar parts held together by special bonds.
Methodology
The compound was synthesized using a Knoevenagel condensation reaction and analyzed using X-ray crystallography.
Digital Object Identifier (DOI)
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