(2-Chloro-3,5-dinitrophenyl)(piperidin-1-yl)methanone
2011
Study of a New Compound with Antibacterial Properties
publication
Evidence: moderate
Author Information
Author(s): Luo Xun, Huang Yun-Chuang, Gao Chao, Yu Luo-Ting
Primary Institution: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University
Hypothesis
The title compound is a key intermediate in the synthesis of antibacterial drugs.
Conclusion
The crystal structure of the compound shows significant intermolecular interactions that may contribute to its properties.
Supporting Evidence
- The piperidine ring adopts a chair conformation.
- One of the nitro groups is almost coplanar with the aromatic ring.
- The crystal packing is stabilized by intermolecular π–π stacking interactions.
Takeaway
Scientists created a new chemical compound that might help fight bacteria, and they studied its structure to understand how it works.
Methodology
The compound was synthesized and its crystal structure was analyzed using X-ray diffraction.
Digital Object Identifier (DOI)
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