Diagnosis and treatment of chronic constipation – a European perspective
2011

Diagnosis and Treatment of Chronic Constipation – A European Perspective

Sample size: 10000 publication Evidence: moderate

Author Information

Author(s): Jan Tack, Stefan Müller-Lissner, Vincenzo Stanghellini, Guy Boeckxstaens, Michael A Kamm, Magnus Simren, Jean-Paul Galmiche, Michael Fried

Primary Institution: University Hospital Leuven

Conclusion

Chronic constipation is common and can significantly affect quality of life, but many patients remain dissatisfied with current treatment options.

Supporting Evidence

  • Chronic constipation affects between 2% and 27% of the population.
  • 14.7% of respondents in a US survey met the criteria for constipation.
  • Only 27% of European patients with chronic constipation are satisfied with current treatment options.

Takeaway

Many people have constipation, and it can be really uncomfortable. Doctors are trying to find better ways to help people feel better.

Methodology

The article reviews the pathophysiology, diagnosis, and management of chronic constipation, including recent therapeutic agents.

Potential Biases

Potential conflicts of interest due to authors' advisory roles with pharmaceutical companies.

Limitations

The evidence for many older laxatives is limited, and treatment is often based on empirical approaches.

Participant Demographics

The study includes a diverse population with chronic constipation, including both men and women.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1111/j.1365-2982.2011.01709.x

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