Immunomodulatory Polysaccharide from Chlorophytum borivilianum Roots
2011

Immunomodulatory Effects of Chlorophytum borivilianum Roots

Sample size: 72 publication Evidence: moderate

Author Information

Author(s): Mayank Thakur, Paul Connellan, Myrna A. Deseo, Carol Morris, Vinod K. Dixit

Primary Institution: Southern Cross University

Hypothesis

The polysaccharide fraction from Chlorophytum borivilianum enhances natural killer cell activity and immune function.

Conclusion

The study found that the polysaccharide fraction from Chlorophytum borivilianum significantly improves immune function and natural killer cell activity.

Supporting Evidence

  • The polysaccharide fraction significantly stimulated NK cell activity.
  • C. borivilianum extract improved humoral immune response as evidenced by increased antibody levels.
  • The study confirmed the non-toxic nature of the C. borivilianum extract.

Takeaway

This study shows that a plant called Chlorophytum borivilianum can help our body's immune system work better.

Methodology

The study involved in vitro and in vivo experiments to evaluate the effects of different fractions of Chlorophytum borivilianum on immune responses in rats and human cells.

Limitations

The study primarily focused on animal models, and further research is needed to confirm findings in humans.

Participant Demographics

Wistar strain albino rats, either sex, weighing 160–180 g.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/ecam/neq012

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