Dramatic Response of Nail Psoriasis to Infliximab
2011
Dramatic Response of Nail Psoriasis to Infliximab
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Safa Gilles, Darrieux Laure
Primary Institution: Centre Hospitalier de Saint-Brieuc
Hypothesis
Can infliximab effectively treat disabling nail psoriasis?
Conclusion
Infliximab showed remarkable and rapid effectiveness in treating psoriatic nail disease.
Supporting Evidence
- Infliximab is a chimeric monoclonal antibody that inhibits TNFα.
- The patient had previously been treated with topical therapies without success.
- After starting infliximab, a dramatic improvement was observed after the second infusion.
Takeaway
A farmer with nail psoriasis got better really fast after taking a medicine called infliximab.
Methodology
The patient was treated with infliximab at a dose of 5 mg/kg administered at weeks 0, 2, and 6.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
A 34-year-old male farmer with a history of stable localized plaque psoriasis.
Digital Object Identifier (DOI)
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