Body Composition Change and Physical Function After Intensive Behavioral Weight Loss Intervention
Author Information
Author(s): Chae Kacey, Bettencourt Amie, Houston Denise, Simonsick Eleanor, Ferrucci Luigi, Kalyani Rita, Clark Jeanne, Gudzune Kimberly
Primary Institution: Johns Hopkins University School of Medicine
Hypothesis
Does body composition change during intensive lifestyle intervention affect physical function in older adults?
Conclusion
Weight loss through intensive lifestyle intervention can improve physical function, particularly when accompanied by fat mass loss, despite some loss of lean mass.
Supporting Evidence
- Participants lost an average of 9.2% of their weight.
- Physical function scores improved in groups with significant fat mass loss.
- Lean mass loss did not significantly affect physical function scores.
Takeaway
When people lose weight, especially fat, they can feel better and move better, even if they lose some muscle.
Methodology
Secondary analysis of the LookAHEAD trial data using dual-energy X-ray absorptiometry to assess body composition and self-reported physical function.
Limitations
The study is limited to participants from the LookAHEAD trial, which may not be generalizable to all populations.
Participant Demographics
Participants had a mean age of 58.3 years, with 63% being women.
Statistical Information
P-Value
p=0.02; p=0.04; p=0.06
Statistical Significance
p=0.02; p=0.04; p=0.06
Digital Object Identifier (DOI)
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