Ertapenem's Effectiveness Against Community-Acquired Bacteremia
Author Information
Author(s): Lee Sai-Cheong, Huang Shie-Shian, Lee Chao-Wei, Fung Chang-Phone, Lee Ning, Shieh Wen-Bin, Siu LK
Primary Institution: Chang Gung Memorial Hospital, Keelung, Taiwan
Hypothesis
The study aims to assess the in vitro activity of ertapenem against aerobic and facultative bacterial pathogens isolated from patients with community-acquired bacteremia.
Conclusion
Ertapenem is highly effective against many bacterial pathogens associated with community-acquired bacteremia.
Supporting Evidence
- Ertapenem was effective against 80.5% of the bacterial isolates tested.
- All enterobacteriaceae isolates, including ESBL strains, were susceptible to ertapenem.
- Ertapenem showed more potent activity than ceftriaxone and piperacillin-tazobactam against methicillin-susceptible S. aureus.
Takeaway
Ertapenem is a strong medicine that works well against germs that can cause serious infections in people who are not sick from other diseases.
Methodology
The study identified bacteria from blood samples of hospitalized patients and tested their susceptibility to various antibiotics using Etest.
Limitations
The study only included patients from one hospital and may not represent all community-acquired bacteremia cases.
Participant Demographics
70 males and 89 females, ages ranged from 1 to 95 years, with a mean age of 60.9 years.
Digital Object Identifier (DOI)
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