Prolonged hemophagocytic lymphohistiocytosis syndrome as an initial presentation of Hodgkin lymphoma: a case report
2008

Case of Hemophagocytic Lymphohistiocytosis Linked to Hodgkin Lymphoma

Sample size: 1 publication Evidence: low

Author Information

Author(s): Chan Kathryn, Behling Eric, Strayer David S, Kocher William S, Dessain Scott K

Primary Institution: Cardeza Foundation for Hematologic Research and Kimmel Cancer Center

Conclusion

Fulminant hemophagocytic lymphohistiocytosis may follow a prodromal phase that resembles chronic hemophagocytic lymphohistiocytosis and should be considered in cases of chronic pancytopenia.

Supporting Evidence

  • The patient had a 3-year history of symptoms suggestive of chronic hemophagocytic lymphohistiocytosis.
  • She was diagnosed with stage IV classical Hodgkin lymphoma.
  • Her condition rapidly progressed, leading to multi-system organ failure.

Takeaway

A woman had a serious immune condition that was linked to a type of cancer called Hodgkin lymphoma, which caused her blood counts to drop dangerously low.

Methodology

Case report detailing the clinical presentation, diagnosis, and treatment of a patient with hemophagocytic lymphohistiocytosis and Hodgkin lymphoma.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

57-year-old Caucasian woman.

Digital Object Identifier (DOI)

10.1186/1752-1947-2-367

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication