Carbohydrate Reward and Psychosis: An Explanation For Neuroleptic Induced Weight Gain and Path to Improved Mental Health?
2011

Carbohydrate Reward and Psychosis: Understanding Weight Gain from Antipsychotics

publication Evidence: moderate

Author Information

Author(s): Simon Thornley, Bruce Russell, Rob Kydd

Primary Institution: The University of Auckland

Hypothesis

Can carbohydrate modified diets improve mental health in people with psychosis?

Conclusion

The study suggests that modifying carbohydrate intake may help reduce psychotic symptoms and weight gain associated with antipsychotic medications.

Supporting Evidence

  • Dopamine release in the brain is linked to both addiction and psychosis.
  • Carbohydrate consumption may activate the same reward pathways as drugs of abuse.
  • Weight gain is a common side effect of antipsychotic medications.

Takeaway

Eating too many carbs might make people with mental health issues feel worse, and changing their diet could help them feel better.

Methodology

The paper reviews existing literature and theories linking dopamine, addiction, and psychosis, proposing dietary modifications as a potential treatment.

Limitations

The theory has not been extensively tested in clinical trials, and dietary interventions may be difficult to implement in patients with schizophrenia.

Digital Object Identifier (DOI)

10.2174/157015911795596513

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