Monitoring Barbiturate Coma in Children with the Bispectral Index Monitor
Author Information
Author(s): Prins Sandra A, de Hoog Matthijs, Blok Joleen H, Tibboel Dick, Visser Gerhard H
Primary Institution: Erasmus MC, University Medical Center, Sophia Children's Hospital
Hypothesis
The BIS monitor can be used to continuously monitor the suppression ratio during barbiturate-induced coma in children.
Conclusion
The BIS monitor provides continuous data on EEG suppression but should be used with caution due to moderate correlations with full-channel EEG.
Supporting Evidence
- The BIS monitor provides continuous data on EEG suppression.
- Correlations between BIS and EEG suppression ratios were moderate.
- Monitoring with BIS is easier for nurses and physicians.
Takeaway
Doctors used a special monitor to check how well kids were responding to medicine that puts them in a deep sleep, and found it helps but isn't perfect.
Methodology
A prospective observational pilot study comparing BIS suppression ratios with full-channel EEG in children with barbiturate-induced coma.
Potential Biases
Potential underestimation of BIS suppression ratios due to differences in algorithms and asymmetrical EEGs.
Limitations
The study had a small sample size and did not monitor EEGs continuously due to organizational limitations.
Participant Demographics
Eight children aged 4 months to 15 years, with conditions like traumatic brain injury and generalized convulsive status epilepticus.
Statistical Information
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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