Disparities in PrEP use and unmet need across PEPFAR-supported programs: doubling down on prevention to put people first and end AIDS as a public health threat by 2030
2024

Disparities in PrEP Use and Unmet Need in PEPFAR Programs

Sample size: 48 publication 10 minutes Evidence: high

Author Information

Author(s): Trena I. Mukherjee, Mitchell Yep, Megan Koluch, Sisay Alemayehu Abayneh, Gizachew Eyassu, Elizabeth Manfredini, Sara Herbst

Primary Institution: USAID

Hypothesis

What are the disparities in PrEP provision across PEPFAR-supported countries?

Conclusion

PrEP use relative to population need varied greatly by country and subpopulation across PEPFAR programs, indicating a need for improved access and tailored prevention strategies.

Supporting Evidence

  • In FY23, 1,760,888 people initiated PrEP, but 1,736,144 tested positive for HIV.
  • 40% of countries had fewer PrEP users than positive HIV tests.
  • Adolescents and young people had the highest median PrEP-to-need ratio.

Takeaway

This study looks at how many people need PrEP to prevent HIV and how many are actually getting it, showing that many people still need help to access it.

Methodology

Analyzed FY2023 Monitoring, Evaluation, and Reporting results from 48 PEPFAR-supported countries to calculate PrEP-to-need ratios.

Potential Biases

Key population status is self-reported, which may under-report actual numbers due to stigma and discrimination.

Limitations

Data is reported cross-sectionally and in aggregate, which may lead to duplication and underestimation of PrEP use.

Participant Demographics

Included various populations such as adolescents, young people, and key populations like sex workers and men who have sex with men.

Digital Object Identifier (DOI)

10.3389/frph.2024.1488970

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