Magnesium intake and serum magnesium concentration in children with type 1 diabetes mellitus: association with glycemic control and clinical symptoms
2024

Magnesium and Type 1 Diabetes in Children

Sample size: 117 publication 10 minutes Evidence: moderate

Author Information

Author(s): Dobrovolska Lesya, Boyarchuk Oksana

Primary Institution: I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine

Hypothesis

The study aimed to determine dietary magnesium intake, serum magnesium concentration in children with type 1 DM, and their impact on the clinical course of DM.

Conclusion

Lower serum magnesium levels in children with type 1 DM were associated with poor glycemic control and more frequent symptoms like headaches and attention deficits.

Supporting Evidence

  • 46% of patients with DM had insufficient magnesium intake.
  • Serum magnesium concentration was significantly lower in children with DM compared to healthy children.
  • Hypomagnesemia was more frequent in children from rural areas.
  • Children with hypomagnesemia had poorer glycemic control.
  • Headaches and attention disorders were more common in DM patients with hypomagnesemia.

Takeaway

Kids with type 1 diabetes often don't get enough magnesium, which can make their diabetes harder to control and cause headaches.

Methodology

This case-control study involved 50 children with type 1 DM and 67 healthy children, assessing dietary intake and measuring serum magnesium levels.

Limitations

The small sample size and single-center design limit the generalizability of the findings.

Participant Demographics

Children aged 6–17 years, including 62% boys in the DM group.

Statistical Information

P-Value

p = 0.011

Confidence Interval

95% CI: 1.7788–20.3440

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fnut.2024.1477814

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