PREFER Trial: Remote Monitoring of Pacemakers
Author Information
Author(s): Chen Jane, Wilkoff Bruce L, Choucair Wassim, Cohen Todd J, Crossley George H, Johnson W Ben, Mongeon Luc R, Serwer Gerald A, Sherfesee Lou
Primary Institution: Washington University School of Medicine
Hypothesis
Quarterly device monitoring by remote interrogation will result in the earlier diagnosis of clinically actionable events compared to the combination of TTM and routine office visits.
Conclusion
The PREFER trial aims to show that remote monitoring of pacemakers can lead to earlier detection of important clinical events.
Supporting Evidence
- Remote monitoring systems allow for full device interrogation while the patient is at home.
- The study aims to improve the management of pacemaker patients by detecting clinically actionable events earlier.
- The trial involves 980 patients randomized to two different monitoring methods.
Takeaway
This study is about using the internet to check pacemakers from home, which might help doctors find problems faster.
Methodology
A prospective, randomized, parallel, unblinded, multicenter, open label clinical trial comparing remote pacemaker interrogation to transtelephonic monitoring.
Potential Biases
Potential bias from the unblinded design and the involvement of Medtronic in funding the trial.
Limitations
The study may not account for all variables affecting patient outcomes and relies on the accuracy of remote monitoring technology.
Participant Demographics
Patients were enrolled from 50 investigative centers in the United States, aged at least 30 days post-system modification.
Statistical Information
P-Value
p<0.05
Confidence Interval
null
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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