Case Report on Treating Recurrent Pancreatic Cancer with Advanced Radiotherapy
Author Information
Author(s): Muacevic Alexander, Adler John R, Forghani Farnoush, D'Souza Alden, Laugeman Eric, MO Allen, Samson Pamela P, Kim Hyun
Primary Institution: Washington University School of Medicine, Saint Louis, USA
Hypothesis
Can cone beam computed tomography-guided adaptive radiotherapy improve treatment outcomes for post-operative recurrent pancreatic cancer?
Conclusion
The use of HyperSight imaging in CT-guided adaptive radiotherapy improved the quality of treatment for a patient with post-operative recurrent pancreatic cancer.
Supporting Evidence
- The patient received nine cycles of neoadjuvant mFOLFIRINOX followed by a Whipple resection.
- Post-surgery, a local recurrence was treated with adaptive stereotactic body radiotherapy at 50 Gy in five fractions.
- The study highlights the utility of HyperSight CBCT for organ-at-risk and tumor delineation.
Takeaway
This study shows that a special type of radiation therapy helped a woman with pancreatic cancer after surgery, making her treatment better and safer.
Methodology
The patient underwent CT-guided adaptive radiotherapy using HyperSight imaging for daily delineation of organs-at-risk and tumor targeting.
Limitations
The study lacks a dosimetric comparison with a similar case treated by an MRI-guided adaptive radiotherapy modality.
Participant Demographics
61-year-old female with post-operative recurrent pancreatic cancer.
Digital Object Identifier (DOI)
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