Artificial Sweeteners and Breast Cancer: A Review
Author Information
Author(s): Yu Xianqiang, Yu Zeng, Chen Xiaoli, Liu Meijun, Yang Feng, Cheung Kenneth C. P.
Primary Institution: Phenome Research Center, School of Chinese Medicine, Hong Kong Baptist University
Hypothesis
What is the relationship between artificial sweeteners and breast cancer risk?
Conclusion
The relationship between artificial sweeteners and breast cancer remains unclear, with some studies suggesting a potential increase in risk through various mechanisms.
Supporting Evidence
- Some studies have reported an increased risk of breast cancer with higher artificial sweetener consumption.
- Certain artificial sweeteners may disrupt hormonal balance, potentially influencing breast cancer risk.
- Artificial sweeteners can alter gut microbiota, which may impact cancer risk through inflammation and metabolic changes.
Takeaway
This study looks at whether artificial sweeteners might cause breast cancer. Some research says they could be linked, but we need more studies to be sure.
Methodology
This review synthesizes existing literature on artificial sweeteners and breast cancer risk, examining various studies and proposed mechanisms.
Potential Biases
Potential selection bias due to non-representative participant samples and reliance on self-reported data.
Limitations
Many studies are observational and may not establish causality; individual responses and study design heterogeneity complicate conclusions.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website