Risk Factors for Surgical Wound Infection and Fascial Dehiscence After Open Gynecologic Surgery
Author Information
Author(s): Hagedorn Carolin, Dornhöfer Nadja, Aktas Bahriye, Weydandt Laura, Lia Massimiliano
Primary Institution: University Hospital of Leipzig
Hypothesis
What are the key risk factors associated with surgical site infections and fascial dehiscence in patients with gynecological cancer undergoing open surgery?
Conclusion
The study found that the duration of surgery significantly affects the risk of surgical site infections and fascial dehiscence, particularly when bowel surgery is involved.
Supporting Evidence
- 50 out of 204 patients developed surgical site infections, indicating a 24.5% incidence.
- 18 patients experienced fascial dehiscence, which is 8.8% of the cohort.
- The duration of surgery was significantly associated with wound complications when bowel surgery was performed.
- Younger patients showed a steeper increase in SSI risk with higher BMI compared to older patients.
Takeaway
This study looked at women with gynecological cancer and found that longer surgeries can lead to more infections, especially if bowel surgery is done.
Methodology
A retrospective cohort study was conducted on patients who underwent median laparotomy for gynecological cancer from January 2017 to December 2020, using machine learning and multivariable logistic regression for analysis.
Potential Biases
Potential biases include the retrospective design and exclusion of certain patient groups.
Limitations
The study is retrospective, has a small sample size, and lacks follow-up data beyond 30 days post-operation.
Participant Demographics
The cohort consisted of 204 women with gynecological malignancies, including cervical, endometrial, and ovarian cancers.
Statistical Information
P-Value
p = 0.013 for BMI effect on SSI, p = 0.024 for bowel surgery effect on SSI, p = 0.007 for operation time effect on FD.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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