Time trend and age-period-cohort effect on kidney cancer mortality in Europe, 1981–2000
2006

Kidney Cancer Mortality Trends in Europe (1981–2000)

publication Evidence: moderate

Author Information

Author(s): Pérez-Farinós Napoleón, López-Abente Gonzalo, Pastor-Barriuso Roberto

Primary Institution: Madrid Public Health Institute

Hypothesis

The study examines the influence of age, death period, and birth cohort on kidney cancer mortality trends across Europe.

Conclusion

Kidney cancer mortality trends in Europe show a clear north-south pattern, with decreasing rates in the north and increasing rates in the south and east.

Supporting Evidence

  • Mortality rates were higher in men than in women across all countries studied.
  • The highest mortality rates were observed in Hungary, Austria, and Nordic countries.
  • Age-adjusted mortality rates showed significant annual decreases in northern Europe.

Takeaway

This study looked at how many people died from kidney cancer in different parts of Europe over 20 years and found that it's getting better in some places but worse in others.

Methodology

The study analyzed kidney cancer deaths and population estimates from the WHO Mortality Database, calculating age- and period-adjusted mortality rates and fitting log-linear Poisson models.

Potential Biases

Potential biases may arise from the exclusion of certain countries and the reliance on mortality data.

Limitations

Some countries were excluded due to incomplete data, which may affect the comprehensiveness of the findings.

Participant Demographics

The study included data from fourteen European countries, focusing on both men and women.

Statistical Information

P-Value

<0.001

Confidence Interval

95% CI 17 to 22%

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1471-2458-6-119

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