Measuring Heart Output in Lambs with Lung Water Issues
Author Information
Author(s): Nusmeier A, Vrancken S, Van der Hoeven JG, Lemson J
Primary Institution: Radboud University Nijmegen Medical Centre
Hypothesis
High levels of extravascular lung water affect the reliability of cardiac output measurement using the transpulmonary thermodilution technique.
Conclusion
Cardiac output can be reliably measured using the transpulmonary thermodilution technique even when extravascular lung water levels are high.
Supporting Evidence
- The study analyzed 62 simultaneous measurements in 11 lambs.
- The correlation coefficient between the COMPA and COTPTD was 0.93.
- The mean bias in the Bland-Altman analysis was -0.09 l/minute.
Takeaway
This study shows that we can still measure how well the heart is pumping in lambs, even when their lungs are filled with extra fluid.
Methodology
Anesthetized lambs were measured for cardiac output using transpulmonary thermodilution and compared with ultrasound measurements.
Participant Demographics
Lambs with a mean body weight of 8.6 kg.
Digital Object Identifier (DOI)
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