Antibiotic Resistance of Atopobium vaginae
Author Information
Author(s): De Backer Ellen, Verhelst Rita, Verstraelen Hans, Claeys Geert, Verschraegen Gerda, Temmerman Marleen, Vaneechoutte Mario
Primary Institution: Ghent University Hospital, UGent, Ghent, Belgium
Hypothesis
What is the antibiotic susceptibility profile of Atopobium vaginae compared to other vaginal bacteria?
Conclusion
Clindamycin is more effective against G. vaginalis and A. vaginae than metronidazole, but not all A. vaginae isolates are resistant to metronidazole.
Supporting Evidence
- All nine strains of A. vaginae were highly resistant to nalidixic acid and colistin.
- Clindamycin inhibited A. vaginae at low concentrations.
- Metronidazole resistance was variable among A. vaginae strains.
Takeaway
This study looked at how well different antibiotics work against a bacteria called Atopobium vaginae, which can cause infections. It found that one antibiotic, clindamycin, works better than another, metronidazole, for treating this infection.
Methodology
Nine strains of Atopobium vaginae and other vaginal bacteria were tested against 15 antibiotics using the Etest method.
Limitations
The study only tested a limited number of strains and may not represent all A. vaginae isolates.
Digital Object Identifier (DOI)
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