1-(4-Chlorophenyl)-3-(2-methoxyanilino)propan-1-one
2011
Study of a Chemical Compound with Antimicrobial Properties
publication
Evidence: moderate
Author Information
Author(s): Ligia Llovera, Pavel Anzenbacher, Simón E. López, Teresa González
Primary Institution: Universidad Simon Bolivar
Hypothesis
The title compound was prepared as an intermediate for the synthesis of 4-aryl-8-methoxy-quinoline under acid conditions.
Conclusion
The compound exhibits a bowed conformation and forms chains in the crystal structure through hydrogen bonding.
Supporting Evidence
- The molecule adopts a slightly angular conformation with a dihedral angle of 39.9°.
- Hydrogen bonds create infinite chains in the crystal structure.
- Weak π–π stacking interactions were also observed in the crystal.
Takeaway
Scientists made a new chemical that can help fight germs, and they found out how it looks and how it sticks together.
Methodology
The compound was synthesized and its crystal structure was determined using X-ray diffraction.
Digital Object Identifier (DOI)
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