Mapping the current trends and hotspots of extracellular vesicles in Alzheimer's disease: a bibliometric analysis
2024

Trends and Hotspots of Extracellular Vesicles in Alzheimer's Disease

Sample size: 602 publication Evidence: high

Author Information

Author(s): Xing Xiaolian, Liu Hongwei, Zhang Minheng, Li Yang

Primary Institution: First Hospital of Shanxi Medical University

Hypothesis

This study aims to elucidate and synthesize the relationship between extracellular vesicles (EVs) and Alzheimer's disease (AD).

Conclusion

Research on microRNA dysregulation, oxidative stress, carboxyl-terminal fragments, small EVs, and mesenchymal stem cell-derived EVs represents a critical frontier in the study of Alzheimer's disease.

Supporting Evidence

  • China and the United States are leading in research on extracellular vesicles in Alzheimer's disease.
  • The National Institute on Aging produced the highest number of publications in this field.
  • MicroRNA dysregulation and oxidative stress are identified as key areas for future research.

Takeaway

Scientists studied a lot of papers about tiny bubbles called extracellular vesicles that might help us understand and treat Alzheimer's disease better.

Methodology

The study used bibliometric techniques to analyze 602 publications from the Web of Science database, focusing on research performance and trends.

Limitations

The study only included English-language papers from the WoS database, potentially missing relevant research published in other languages.

Digital Object Identifier (DOI)

10.3389/fnagi.2024.1485750

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