Carlow Virus, a 2002 GII.4 variant Norovirus strain from Ireland
2007

Carlow Virus: A New Norovirus Strain from Ireland

Sample size: 70 publication Evidence: moderate

Author Information

Author(s): Kearney Karen, Menton John, Morgan John G

Primary Institution: University College Cork

Hypothesis

What is the genetic makeup of the Carlow virus, a new variant of Norovirus found in Ireland?

Conclusion

Carlow virus is a member of the Farmington Hills variant cluster of Genogroup II genotype 4 noroviruses.

Supporting Evidence

  • Noroviruses are the leading cause of infectious non-bacterial gastroenteritis in Ireland.
  • The Carlow virus genome is 7559 nucleotides long and represents the first Norovirus strain from Ireland to be sequenced.
  • 32 out of 70 stool samples tested positive for Norovirus, with 28 belonging to Genogroup II.

Takeaway

Scientists studied stool samples from sick people to find a new type of virus called Carlow virus, which makes people sick in Ireland.

Methodology

The study involved screening 70 stool samples from five hospital outbreaks to identify the prevalent Norovirus genotype, followed by cloning the virus genome.

Limitations

Research on Norovirus strains in Ireland is still at a preliminary stage.

Participant Demographics

Samples were taken from symptomatic individuals suspected to harbor Norovirus in a hospital setting.

Digital Object Identifier (DOI)

10.1186/1743-422X-4-61

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