Design of the BRISC study: a multicentre controlled clinical trial to optimize the communication of breast cancer risks in genetic counselling
2008

BRISC Study: Improving Breast Cancer Risk Communication

Sample size: 450 publication Evidence: moderate

Author Information

Author(s): Ockhuysen-Vermey Caroline F, Henneman Lidewij, van Asperen Christi J, Oosterwijk Jan C, Menko Fred H, Timmermans Daniƫlle RM

Primary Institution: VU University Medical Center, Amsterdam, the Netherlands

Hypothesis

What is the effect of different formats of risk communication on women's understanding and decision-making regarding breast cancer risks?

Conclusion

The BRISC study aims to evaluate how different ways of communicating breast cancer risks can improve women's understanding and decision-making.

Supporting Evidence

  • Understanding risks is crucial for informed decision-making.
  • Inaccurate risk perception is common among women with a family history of breast cancer.
  • The study evaluates the effects of different risk communication formats.
  • Results may improve risk communication in genetic counselling.
  • Participants are women with a family history of breast cancer.
  • The study includes a control group for comparison.
  • Sample size is determined to detect clinically relevant differences.
  • Randomisation is applied to minimize bias.

Takeaway

This study is trying to find the best way to explain breast cancer risks to women so they can make better choices about their health.

Methodology

The study is a pre-post-test controlled group intervention trial using questionnaires to measure outcomes.

Potential Biases

Selection bias is limited, but self-selection may occur.

Limitations

The study cannot completely blind genetic counsellors, and there may be factors other than risk that influence decision-making.

Participant Demographics

Women with a family history of breast cancer attending genetic counselling.

Digital Object Identifier (DOI)

10.1186/1471-2407-8-283

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