Fermented Wheat Germ Extract in Colorectal Cancer Treatment
Author Information
Author(s): Jakab F, Shoenfeld Y, Balogh Á, Nichelatti M, Hoffmann A, Kahán Zs, Lapis K, Mayer Á, Sápy P, Szentpétery F, Telekes A, Thurzó L, Vágvölgyi A, Hidvégi M
Primary Institution: Uzsoki Teaching Hospital of Budapest, Hungary
Hypothesis
Does the addition of fermented wheat germ extract (MSC) to standard anticancer treatments improve progression-free survival in colorectal cancer patients?
Conclusion
The study found that adding MSC to standard treatments may inhibit tumor progression and prolong survival in colorectal cancer patients.
Supporting Evidence
- Patients receiving MSC had significantly fewer new recurrent diseases compared to the control group.
- The MSC group had a lower percentage of new metastatic lesions than the control group.
- Deaths were significantly less frequent in the MSC cohort compared to the control cohort.
Takeaway
This study looked at whether a wheat extract could help people with colon cancer live longer and have fewer problems from their cancer treatments.
Methodology
An open-label, multicentre cohort study comparing progression-free survival between patients receiving standard treatments alone and those receiving treatments supplemented with MSC.
Potential Biases
The treatment assignment was based on patient preference, which may introduce selection bias.
Limitations
The study design was not randomized, leading to unbalanced cohorts based on patient preference.
Participant Demographics
Patients included 66 in the MSC group and 104 in the control group, with a mean age of 61.7 years for MSC and 66.1 years for control.
Statistical Information
P-Value
P<0.001
Confidence Interval
1.37–2.98
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website