The Anatomical and Functional Outcome of Autologous Internal Limiting Membrane Transplant With 27-Gauge Vitrectomy in Failed and Recurrent Macular Holes in a Spectrum of Pathologies
2024

Outcomes of ILM Transplant in Macular Holes

Sample size: 7 publication Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Mohsin Fatima, Awan Muhammad Amer

Primary Institution: Shifa International Hospitals Limited, Islamabad, PAK

Hypothesis

To describe the anatomical and functional outcome of autologous internal limiting membrane (ILM) transplant with 27-gauge plus vitrectomy in failed and recurrent macular holes.

Conclusion

An autologous ILM transplant with a 27G+ PPV is an effective technique for closing macular holes in complicated cases.

Supporting Evidence

  • All patients had successful surgery with closure of macular holes postoperatively.
  • Mean best corrected visual acuity improved significantly from 1.60 to 0.60 over 12 months.
  • One patient experienced a retinal re-detachment but was successfully managed.

Takeaway

Doctors used a special technique to help fix holes in people's eyes, and it worked really well for everyone in the study.

Methodology

Observational cohort study involving seven patients who underwent surgery for failed or recurrent macular holes.

Limitations

Limited sample size and retrospective nature of the study.

Participant Demographics

Average age of participants was 49.4 years, with four males and three females.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7759/cureus.76120

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