Geographic Distribution of Melanoma in Massachusetts
Author Information
Author(s): DeChello Laurie M, Sheehan T Joseph
Primary Institution: University of Connecticut School of Medicine
Hypothesis
Are the geographic variations in melanoma incidence statistically significant or random, and can they be explained by socioeconomic status or urban/rural residence?
Conclusion
The study identifies geographic areas with melanoma incidence that is higher or lower than expected, and how these areas are affected by socioeconomic and urban factors.
Supporting Evidence
- Thirteen geographic areas with significant deviations in melanoma incidence were identified.
- Five areas had higher incidence rates than expected for males, while six areas had higher rates for females.
- Adjustment for socioeconomic status and urban/rural factors reduced the number of significant areas.
Takeaway
This study looked at where melanoma cases happen in Massachusetts and found some areas have more cases than expected, which might be linked to where people live and their income.
Methodology
The study used Poisson regression to analyze melanoma incidence data from the Massachusetts Cancer Registry for cases diagnosed from 1990 to 1999, adjusting for socioeconomic status and urban/rural status.
Potential Biases
Geocoding errors and reliance on residential addresses at diagnosis may not accurately reflect exposure locations.
Limitations
Underreporting of melanoma cases and potential inaccuracies in geocoding addresses may bias the results.
Participant Demographics
The study included 4774 female and 5688 male melanoma cases diagnosed in Massachusetts.
Statistical Information
P-Value
<0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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