(E)-1-[4-(Hexyloxy)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one C21H24O3
2011
Crystal Structure of a Chalcone Derivative
publication
Evidence: moderate
Author Information
Author(s): Ngaini Zainab, Fadzillah Siti Muhaini, Hussain Hasnain, Razak Ibrahim Abdul, Fun Hoong-Kun
Primary Institution: Universiti Malaysia Sarawak
Hypothesis
The study investigates the crystal structure and properties of a synthesized chalcone derivative.
Conclusion
The synthesized chalcone derivative exhibits antimicrobial activity and has a stable crystal structure formed by specific intermolecular interactions.
Supporting Evidence
- The compound showed antimicrobial activity against E. coli ATCC 8739.
- Intermolecular interactions formed bifurcated acceptor bonds generating ring motifs.
- The crystal structure is stabilized by C—H···π interactions.
Takeaway
The researchers made a new compound that can fight germs, and they looked at its structure to understand how it works.
Methodology
The compound was synthesized through a reaction of 4-hydroxybenzaldehyde and 4-hexyloxyacetophenone, followed by X-ray crystallography for structural analysis.
Digital Object Identifier (DOI)
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