Association between brominated flame retardants and periodontitis: a large-scale population-based study
2024

Brominated Flame Retardants and Periodontitis

Sample size: 2445 publication 10 minutes Evidence: high

Author Information

Author(s): Jiang Hao, Yin Jingwen, Wang Meixiang, Yuan Aili, Wu Jing, Lu Yi

Primary Institution: The Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou, China

Hypothesis

Is there an association between brominated flame retardants (BFRs) and periodontitis?

Conclusion

Overall exposure to brominated flame retardants is positively associated with the prevalence of periodontitis.

Supporting Evidence

  • Several ln-transformed BFR components were positively correlated with periodontitis.
  • The WQS index for mixed BFR exposure was positively associated with periodontitis prevalence.
  • QGC analysis showed a positive association between mixed BFR exposure and periodontitis prevalence.

Takeaway

This study found that being around certain chemicals called brominated flame retardants can make people more likely to have gum disease.

Methodology

The study used data from NHANES cycles 2009–2014 and employed survey-weighted generalized linear regressions to analyze the association between BFR exposure and periodontitis.

Potential Biases

Potential unaccounted confounding factors may influence the results.

Limitations

As a cross-sectional study, it cannot establish a causal relationship between BFR exposure and periodontitis.

Participant Demographics

The average age of participants was 51 years, with 48.85% male.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI: 1.30–1.79

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.3389/fpubh.2024.1476953

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