Clinical Implication of Coronary Tortuosity in Patients with Coronary Artery Disease
Author Information
Author(s): Li Yang, Shen Chengxing, Ji Yanan, Feng Yi, Ma Genshan, Liu Naifeng
Primary Institution: Zhongda Hospital, Southeast University, Nanjing, China
Hypothesis
The study investigates the clinical characteristics of coronary tortuosity in patients with suspected coronary artery disease.
Conclusion
Coronary tortuosity is more common in females and is positively correlated with hypertension but negatively correlated with coronary atherosclerosis.
Supporting Evidence
- The prevalence of coronary tortuosity was found to be 39.1% in the study cohort.
- Coronary tortuosity was significantly higher in females compared to males.
- Patients with coronary tortuosity had a higher incidence of essential hypertension.
Takeaway
Coronary tortuosity is when the arteries twist and turn more than normal, and it happens more in women and people with high blood pressure.
Methodology
The study included 1010 patients who underwent coronary angiography and were followed for 2 to 4 years.
Limitations
The study did not evaluate hemodynamic changes and had a relatively small patient number with a short follow-up time.
Participant Demographics
544 males, mean age 64±11 years; 39.1% prevalence of coronary tortuosity.
Statistical Information
P-Value
p<0.001
Confidence Interval
95%CI 1.897, 3.607
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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