Plummer-Vinson syndrome
2006
Plummer-Vinson Syndrome Overview
publication
Evidence: low
Author Information
Author(s): Novacek Gottfried
Primary Institution: Medical University of Vienna
Conclusion
Plummer-Vinson syndrome is a rare condition characterized by dysphagia, iron-deficiency anemia, and esophageal webs, with an increased risk of upper gastrointestinal cancers.
Supporting Evidence
- Plummer-Vinson syndrome is associated with an increased risk of squamous cell carcinoma of the pharynx and esophagus.
- Symptoms include painless dysphagia, weakness, and fatigue due to anemia.
- Iron supplementation can effectively treat the dysphagia in many patients.
Takeaway
Plummer-Vinson syndrome makes it hard to swallow and can lead to anemia. It's important to treat it with iron and sometimes surgery.
Limitations
Exact data on incidence and prevalence are not available, and the syndrome is extremely rare today.
Participant Demographics
Most patients are white middle-aged women, but it can also occur in children and adolescents.
Digital Object Identifier (DOI)
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