Obesity and Intracranial Hemorrhage Outcomes
Author Information
Author(s): Ng Helen, Huhulea Ellen N., Jain Ankita, Fortunato Michael, Subah Galadu, Sacknovitz Ariel, Spirollari Eris, Rosenberg Jon B., Bauerschmidt Andrew, Mayer Stephan A., Gandhi Chirag D., Al-Mufti Fawaz
Primary Institution: New York Medical College
Hypothesis
Does the obesity paradox apply to all forms of intracranial hemorrhage?
Conclusion
Patients with class I–II obesity who experience intracranial hemorrhage have better clinical outcomes than those with a healthy weight.
Supporting Evidence
- Obese patients had a shorter length of stay in the hospital.
- Obese patients had lower inpatient mortality rates.
- Class I–II obesity was associated with more favorable discharge outcomes.
Takeaway
Being a little overweight might actually help some people do better when they have a brain bleed.
Methodology
Data from the National Inpatient Sample was analyzed for patients with non-traumatic intracranial hemorrhage from 2015 to 2019, stratified by BMI.
Potential Biases
Retrospective nature may introduce selection bias and confounding factors.
Limitations
The study relies on BMI as a measure of obesity, which may not accurately reflect body composition.
Participant Demographics
Patients aged 18 and older with a primary diagnosis of non-traumatic intracranial hemorrhage.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 1.052, 1.152
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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